Problems along I-95 Southbound after a tractor trailer loaded with caulking and other industrial adhesives overturns and spills part of its load.
The accident happened just before 10:30 a.m. Wednesday near the Dale City on and off ramps. At least one of the travel lanes is also shut down.
Motorists should use an alternate route and expect delays.
State police says it will take several hours to clean up the mess and upright the rig.
The driver was not injured and the cause of the crash remains under investigation.